Formulation and development and evaluation of microencapsulated suspension of ofloxacin

  • Ch.Saibabu Head , Department of Pharmaceutics, M.L. College of Pharmacy, S. Konda-523101
    saichennupalli@gmail.com
  • M.Swapna Department of Pharmaceutics, M.L. College of Pharmacy, S. Konda-523101

Abstract

The present work is to formulation and evaluation of Ofloxacin of microencapsulated suspension by using solvent evaporation method. The Preparation contains six formulations of suspensions with 2 different polymers with different concentrations as Ofloxacin resinate + HPMC, Ofloxacin resinate + Carbopol 934. The prepared batches of Ofloxacin microencapsulated suspension were evaluated for the pH, viscosity, sedimentation volume; density, drug content and antibacterial activity of all the six formulations were performed. Formulations F-3, F-6 gave better sustained release and antibacterial activity. Comparative study of F-3, F-6 with marketed product reveal the F-3 is best fitted formulation for preparation of microencapsulated suspension.

Keywords: Sustained release dosage form (SR), controlled release drug delivery systems (CRDDS), ofloxacin

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Published
19/10/2021
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How to Cite
[1]
S. Ch and S. M, “Formulation and development and evaluation of microencapsulated suspension of ofloxacin ”, Int J Indig Herb Drug, vol. 6, no. 5, pp. 93-100, Oct. 2021.
Section
Research Articles