International Journal of Indigenous Herbs and Drugs

Evaluation of antibacterial property of anthyocyanin extracted from brassica oleracea against gram positive and gram negative bacteria by using erythromycin as a standard drug.

2023-03-20T10:03:16+0530

Anthocyanin was extracted from Brassica oleracea and identified by UV and TLC.The benzene test initially helps us to identify Anthocyanin in residue. Crystals were purified by recrystallization from ether. Acetone –petroleum ether extraction resulted in higher crude Anthocyanin yield than hexane extraction The compounds were tested against two microorganisms namely E. coli (gram-ve) and bacillus (gram+ve) and the compounds showed significant activity against two species. Test sample one Showed significant activity with zone of inhibition (18.21mm). When compared to standard Erythromycin with zone of inhibition (20.83mm) at 100,200,400mg/ml against E. coli organism. Test sample two Showed significant activity with zone of inhibition (15.56mm) when compared to standard Erythromycin with zone of inhibition at (100,200,400mg/ml) against Bacillus.

Premature ovarian insufficiency: an augmenting disorder in the growing female population

2023-03-20T10:03:08+0530

A primary ovarian abnormality such as absent menarche (primary amenorrhea) or early depletion of ovarian follicles/arrested folliculogenesis before the age of 40 is described as premature ovarian insufficiency (secondary amenorrhea). Itsprevalence is 1% and 0.1 % in women under 40 and 30 respectively. Common Symptoms include palpitations, excessive sweating, flushes, anxiety, depression, and fatigue. There could be a variety of causes, including chromosomal abnormalities, autoimmune diseases, infections, idiopathic diseases, iatrogenic diseases, and so on. Diagnosis is usually done based on the level of hormones like estradiol, Follicle Stimulating Harmone, and LuteinizingHarmone. Considering the complications of premature ovarian failure, it is necessary to educate the female population about this disorder. Hence, the Present review focuses on the etiology, symptoms, complications, diagnosis, and treatment of premature ovarian failure.