A review article on pcos and its impact on quality of life in women correlation with age, basal metabolic index and various factors

  • T.Rushinaidu Assistant professor, Department of Pharmacy Practice, Avanti institute of pharmaceutical sciences, vizianagaram
  • G.Eswari Student, Department of Pharmacy Practice, Avanti institute of pharmaceutical sciences, Vizianagaram.
  • L.Satish Kumar achari Student, Department of Pharmacy Practice, Avanti institute of pharmaceutical sciences, Vizianagaram.
  • M.Jnapika Student, Department of Pharmacy Practice, Avanti institute of pharmaceutical sciences, Vizianagaram.
  • L.Krishnapriya Student, Department of Pharmacy Practice, Avanti institute of pharmaceutical sciences, Vizianagaram.


Polycystic ovary syndrome (PCOS) is a hormonal disorder characterised by presence of oligomenorrhoea, anovulation and hyperandrogenism in females. PCOS mainly observed in women in adolescent age to pre-partum resulting in abortions. Symptoms mainly include irregular menstrual cycles, anovulation, acne, hirsutism and oligomenorrhea. The pathophysiology of PCOS involves the primary ovarian abnormalities, endocrine alterations and metabolic modifiers such as anti-Mullerian hormone, insulin resistance and chronic inflammation which causes metabolic disturbances and results hormone imbalance which results in hyperandrogenism therefore development of cysts in ovaries is observed. Diagnostic criteria are mainly done from the Rotterdam criteria of PCOSwhich includes mainly presence of menstrual irregularities, ultrasound scanning and Luteinizing Harmone (LH) and Follicle-stimulating hormone (FSH) ratio and raise of androgens level in body. Treatment options includes oral contraceptive pills, metformin therapy for insulin intolerance, local treatments for hirsutism by laser hair removal therapy, hormone replacement therapy for hyperandrogenism and acne. Non-pharmacological treatment includes diet changes, regular exercises and weight loss. Early diagnosis of PCOD can improve the quality of life and minimize the chances of causing cardiac problemsand further complications caused by PCOS such as hair loss, infertility and if left undiagnosed may result in uterus cancer.

Keywords: oligomenorrhoea, hyperandrogenism, metabolic modifiers, LH, FSH, anti -Mullerian


Download data is not yet available.


1. https://www.asianhomeocare.com/pcod
2. https://www.wikidoc.org/index.php/Polycystic_ovary_syndrome_classification#:~:text=Polycystic%20ovary%20syndrome%20(PCOS)%20may,%2C%20classic%2C%20and%20metabolic%20form
3. Mehreen TS, Ranjani H, Kamalesh R, Ram U, Anjana RM, Mohan V. Prevalence of polycystic ovarian syndrome among adolescents and young women in India. J Diabetol [serial online] 2021 [cited 2022 Dec 8];12:319-25. Available from: https://www.journalofdiabetology.org/text.asp?2021/12/3/319/327299
4. https://sciencetranslated.org/the-psychological-effects-of-pcos/
5. https://journals.lww.com/ijmr/Fulltext/2019/50040/Epidemiology,_pathogenesis,_genetics___management.5.aspx
6. https://emirateshospitals.ae/pcos-symptoms-obstetrics-and
7. https://www.mayoclinic.org/diseases-conditions/pcos/symptoms-causes/syc-20353439
8. Escobar-Morreale, H. Polycystic ovary syndrome: definition, aetiology, diagnosis and treatment. Nat Rev Endocrinol 14, 270–284 (2018). https://doi.org/10.1038/nrendo.2018.24
9. Asian Pac J Cancer Prev. 2017; 18(1): 17–21
10. https://sprintmedical.in/blog/pcod-vs-pcos-differences-causes-symptoms-effects-diagnosis-risks-treatments
11. https://www.uptodate.com/contents/etiology-and-pathophysiology-of-polycystic-ovary-syndrome-in-adolescents
12. https://www.aafp.org/pubs/afp/issues/2016/0715/p106.html
13. Based on Harsh Mohan’s textbook of pathology eighth edition (pathology quick review) pg. no: 450
14. https://www.statpearls.com/ArticleLibrary/viewarticle/27400
15. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737989/
16. https://pubmed.ncbi.nlm.nih.gov/22594862/
17. Urbanek, M. The genetics of the polycystic ovary syndrome. Nat Rev Endocrinol 3, 103–111 (2007). https://doi.org/10.1038/ncpendmet0400
18. https://www.sciencedirect.com/science/article/pii/S266639612100008X
19. https://link.springer.com/article/10.1186/s43042-019-0031-4
20. http://jme.bioscientifica.com/
21. L. Cronin, G. Guyatt, L. Griffith, E. Wong, R. Azziz, W. Futterweit, D. Cook, A. Dunaif, Development of a Health-Related Quality-of-Life Questionnaire (PCOSQ) for Women with Polycystic Ovary Syndrome (PCOS), The Journal of Clinical Endocrinology & Metabolism, Volume 83, Issue 6, 1 June 1998, Pages 1976–1987, https://doi.org/10.1210/jcem.83.6.4990
22. https://www.aafp.org/pubs/afp/issues/2016/0715/p106.html
159 Views | 97 Downloads
How to Cite
T, R., E. G, S. K. achari L, J. M, and K. L. “A Review Article on Pcos and Its Impact on Quality of Life in Women Correlation With Age, Basal Metabolic Index and Various Factors”. International Journal of Health Care and Biological Sciences, Vol. 4, no. 1, Jan. 2023, pp. 13-17, doi:10.46795/ijhcbs.v4i1.409.
Review Articles