International Journal of Health Care and Biological Sciences https://www.saap.org.in/journals/index.php/ijhcbs <p>International Journal of Health Care and Biological Sciences (IJHCBS) is an international online open access, peer-reviewed, quarterly journal Publish Health as well as Life sciences field on the basis of its originality, and serve as a means for scientific information exchange in the international Health Care and Biological science with a strong emphasis on originality and scientific quality. IJHCBS aims to publish quarterly and accepts for publishing original and research articles, review articles, case studies, and reports short communication, meta-analysis.</p> International Journal of Health Care and Biological Sciences en-US International Journal of Health Care and Biological Sciences 2582-7499 A review on: medicated chewing gum https://www.saap.org.in/journals/index.php/ijhcbs/article/view/404 <p>Chewing gums are the type of mobile drug delivery systems. It is useful by means of administering drugs either locally or systemically through, the oral cavity. The treated chewing gum has through the times gained adding acceptance as a medicine delivery system. As compare to that chewable tablets treated epoxies aren't supposed to be swallowed and it can be removed from the point of operation without resort to invasive means and treated biting gum. MCG is solid, single cure medication. The end of this review is to gives an overview of gum composition, manufacturing process, and characterization. Due to the failure of studies concerning the evaluation of the mechanical parcels of MCGs, lesser effect was placed on the available performance tests and procedures for the estimation of their mechanical and textural parcels. It can be used either for original (mucosal) treatment of mouth complaint or for systemic (transmucosal) delivery by direct intra oral immersion through the buccal mucosa.</p> Ashwini Jadhav Copyright (c) 2023 https://creativecommons.org/licenses/by-nc/4.0 2023-01-12 2023-01-12 1 12 10.46795/ijhcbs.v4i1.404 A review article on pcos and its impact on quality of life in women correlation with age, basal metabolic index and various factors https://www.saap.org.in/journals/index.php/ijhcbs/article/view/409 <p>Polycystic ovary syndrome (PCOS) is a hormonal disorder characterised by presence of oligomenorrhoea, anovulation and hyperandrogenism in females. PCOS mainly observed in women in adolescent age to pre-partum resulting in abortions. Symptoms mainly include irregular menstrual cycles, anovulation, acne, hirsutism and oligomenorrhea. The pathophysiology of PCOS involves the primary ovarian abnormalities, endocrine alterations and metabolic modifiers such as anti-Mullerian hormone, insulin resistance and chronic inflammation which causes metabolic disturbances and results hormone imbalance which results in hyperandrogenism therefore development of cysts in ovaries is observed. Diagnostic criteria are mainly done from the Rotterdam criteria of PCOSwhich includes mainly presence of menstrual irregularities, ultrasound scanning and Luteinizing Harmone (LH) and Follicle-stimulating hormone (FSH) ratio and raise of androgens level in body. Treatment options includes oral contraceptive pills, metformin therapy for insulin intolerance, local treatments for hirsutism by laser hair removal therapy, hormone replacement therapy for hyperandrogenism and acne. Non-pharmacological treatment includes diet changes, regular exercises and weight loss. Early diagnosis of PCOD can improve the quality of life and minimize the chances of causing cardiac problemsand further complications caused by PCOS such as hair loss, infertility and if left undiagnosed may result in uterus cancer.</p> Rushinaidu T Eswari G Satish Kumar achari L Jnapika M Krishnapriya L Copyright (c) 2023 https://creativecommons.org/licenses/by-nc/4.0 2023-01-19 2023-01-19 13 17 10.46795/ijhcbs.v4i1.409