Formulation and optimization of synthetic polymer based herbal emulgel for anti-microbial activity

  • Namrata Patel Department of Pharmacy, Goel Institute of Pharmacy and Sciences, Faizabad Road, Lucknow, 226028, Uttar Pradesh, India
    patelnamrata488@gmail.com
  • Nitish Kumar Department of Pharmacy, Goel Institute of Pharmacy and Sciences, Faizabad Road, Lucknow, 226028, Uttar Pradesh, India
  • Arpita Singh Department of Pharmacy, Goel Institute of Pharmacy and Sciences, Faizabad Road, Lucknow, 226028, Uttar Pradesh, India
  • Amresh Gupta Department of Pharmacy, Goel Institute of Pharmacy and Sciences, Faizabad Road, Lucknow, 226028, Uttar Pradesh, India

Abstract

The aim of the present research was to develop and evaluate the anti-microbial emulgel by using three different types of synthetic polymers. The active moiety selected for the formulation was the seeds of Carica papaya fruit. The formulation was developed by performing the extraction process; Soxhlet extraction with ethanol and water. The seeds of Carica papaya are reported to have anti-microbial properties. The skin-friendly i.e., the topical formulation was selected for development. Emulgel was prepared by incorporating different polymers and then evaluating each of them for best results. Basic evaluation parameters such as organoleptic parameters, viscosity, consistency, pH, homogeneity have been done, which demonstrate the results as per the reference and standard articles. Along with that, qualitative and quantitative tests of Carica seeds have also been performed, which indicates that the selected plant material is safe for usage. Finally, the most imp test, the anti-microbial test has been performed for determining the efficacy of prepared emulgel. Hence, it can be concluded that the prepared emulgel is safe and best for topical use as an anti-microbial. 

Keywords: Anti-microbial, emulgel, Carica papaya

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References

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Published
29/09/2021
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How to Cite
Patel, N., Kumar, N., Singh, A., & Gupta, A. (2021). Formulation and optimization of synthetic polymer based herbal emulgel for anti-microbial activity. Journal of Innovations in Applied Pharmaceutical Science (JIAPS), 6(3), 37-42. https://doi.org/10.37022/jiaps.v6i3.217
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Research Article(S)