Journal of Innovations in Applied Pharmaceutical Science (JIAPS) <p><span style="color: #000000;">Journal of Innovations in Applied pharmaceutical Science (JIAPS) is an open access, quarterly, peer-reviewed multi-disciplinary journal; and will publish articles in various streams of pharmaceutical &amp; allied sciences. JIAPS publishes original research and review articles, Mini-reviews, Short communication, Case studies and editorial commentary and news, Opinions &amp; Perspectives and Book Reviews written at the invitation of the Editor in the fields of applied pharmaceutics</span></p> en-US <p>Copyright © Author(s) retain the copyright of this article.</p> (Support) (Tech Support) Sun, 26 Jun 2022 23:03:32 +0530 OJS 60 Chronic kidney disease and its complete scenario, management of chronic kidney disease by clinical pharmacists - a prospective interventional study <p>Chronic kidney disease is a growing epidemic worldwide. Nearly two-thirds of CKD patients have diabetes mellitus, hypertension, and both comorbid conditions. Several disease management programs are developed and they implement with help of physicians, and highly trained clinical pharmacists to improve disease management and improve clinical outcomes. The goals of clinical pharmacist in the management of CKD patients by focusing on Four key areas: To obtain information about medication non-adherence, To assess the patient complications for dialysis, to assess the prevalence of chronic kidney disease patients, To evaluate the clinical pharmacist’s role in improving patient medication adherence, To identify the correlation between CKD and other comorbidities, To observe the drug interactions in prescribed drugs. Lack of patient knowledge on CKD disease conditions, and limited reimbursement, lack of primary care by physicians and health care professionals are all barriers that must be overcome with help of the clinical pharmacist role in the management of CKD.</p> Padma Priya D, Jagadeeshwari K, Prema Kumari N, Abhisekhar M, Uma Sankar V Copyright (c) 2022 Sun, 26 Jun 2022 00:00:00 +0530 Evaluation of quality of life (QOL), depression prevalence and distress in diabetes mellitus diagnosed patients of a tertiary care teaching hospital - a prospective interventional analytical study <p>Diabetic Mellitus is a group of metabolic disorders characterized by hyperglycaemia, which occurs due to defects in insulin secretion, insulin action, or both. Diabetics distress is an emotional distress response characterized by extreme apprehension, discomfort, or dejection due to a perceived inability to cope with the challenges and demands of living with diabetes. The goals of clinical pharmacist is to management of about medication adherence, to evaluate the quality of life, identify depression levels among diabetic patients, to identify anxiety levels in diabetic patients, to evaluate diabetic distress and its effects among diabetics. Diabetic distress is the major problem associated with diabetics which is making patients losing their self-confidence and positive attitude towards life. Due to diabetic distress, depression and anxiety significant percentage of patients work exhibited poor quality of life. Proper counselling, continuous interaction, effective therapy by the clinical pharmacists could improve patients quality of life, diabetes causative and medication adherence.</p> Sanjuna A, K.S.Vasanthasena D, Navyasree M, Akhila P, Hemanthanissi B, UMA SANKAR V, Madhu Chandaka Copyright (c) 2022 Wed, 29 Jun 2022 00:00:00 +0530 Assessment of quality of life in covid-19 patients post recovery- an observational analytical study <p>The novel coronavirus has become rapidly widespread, resulting in an epidemic throughout China followed by a pandemic, an increasing number of cases in various countries throughout the world. During the Post COVID-19 period, the quality of life of several people has been impacted to varying extents. The physical health of the patients has shown a significant decline after getting recovered from COVID-19. We have done a community survey and have assessed the physical health of 400 subjects and have observed that there is a limitation in the physical activities of the subjects.</p> Sai Padmini G, Sumathya P, Ratna Jyothirmai M, Niharika B, Gunasekhar S, Tejasree B Copyright (c) 2022 Wed, 29 Jun 2022 00:00:00 +0530 Identifying the most commonly occurred clinical symptoms of covid-19 patients at southern hospitals and community setting – a retrospective study <p><strong>Background:&nbsp;&nbsp;</strong>The First Case Of A Novel Coronavirus (COVID-19) Infection Was Detected In Wuhan, Fever And Respiratory Symptoms Have Been Frequently Reported In Patients Infected With This Virus.</p> <p><strong>Aim: </strong>It Was Aimed To Detect The Most Commonly Occurred Clinical Symptoms Of COVID19 In Hospitals And Community Settings.</p> <p><strong>Method: </strong>Patients Presenting To Southern Hospitals And Community Settings For COVID-19 Infection Were Included In The Study. Assessment Of Demographics And Background Information Of Covid-19 Infection Is Done And Next The Patients Were Questioned For 22 Symptoms And The Results Were Compared. Listing Out The Symptoms And Symptoms Status And Functionality Status Prior to The Collection Of All Data For Statistical Analysis To Represent The Results.</p> <p><strong>Results: </strong>A Total Of 403 Patients With COVID-19 Positive Status Were Included In The Study. The Most Common Symptoms In The COVID-19 Positive Group Were: Cough (81.9%), Shortness Of Breath (78.7%), Sneezing (77.4%), Fever (91.4%), Headache (89.6%), Loss Of Taste (69.2%), And Muscle Pain (80.1%).</p> <p><strong>Conclusion:&nbsp;</strong>Our Study Showed That Taste And Cough Were Important Markers In COVID-19 Infection.</p> Sai Himabindu Ch, Sreevani K, Tanish B, Madhu Chandaka , Tejasree B Copyright (c) 2022 Tue, 28 Jun 2022 00:00:00 +0530 Molecular identification of chlorpyrifos and Malathion degrading bacteria <p>Fifteen strains of bacteria were successfully isolated from agriculture soil samples contains pesticides and from soil moisture around them. The isolates were capable of utilizing chlorpyrifos (Cp) and malathion as the sole source of carbon, phosphorus and energy. High yielding isolate KSCM-08 was identified based on16SrRNA sequencing. Genomic DNA was successfully extracted from bacterial isolate KSCM-08, and the total DNA content was determined to be 734±23 µg/gm. The absorbance ratio of extracted DNA at A260/280 has been found to be 1.96±0.2. 1381 nucleotide sequence of the PCR amplified 16s rRNA gene from bacterial isolate KSCM-08. The 16s rRNA gene sequence comprises 344 bp of adenine (A), 280 bp of thymine (T), 430 bp of guanine (G), and 327 bp of cytosine (C). The G+C percentage was determined to be 54.8%. The BLAST report demonstrates the similar sequences with the KSCM-08 16s rRNA sequence, along with their percentage of identity. The BLASTn analysis of the 1381 bp length 16s rRNA gene sequence of KSCM-08 against the GenBank database revealed that KSCM-08 exhibits similarity with <em>Bacillus</em> species. The evolutionary divergence of bacterial isolate KSCM-08 with its relative members was determined. A satisfactory result was established by the use of the 16S rRNA gene as a marker to evaluate the phylogenetic relationship and the bacteria was confirmed as <em>Bacillus safensis. </em></p> Sumanjali Avanigadda, Meena Vengalapati Copyright (c) 2022 Wed, 03 Aug 2022 00:00:00 +0530 A study on pharmacovigilance case processing <p>Pharmacovigilance plays an vital role in modern technology which helps in monitoring and assessing the high-quality of Drugs, detection and stopping of any unfavorable outcomes of drugs. Pharmacovigilance starts with case processing: this involve safety data collection and coding, case management reporting and submission. In case of clinical trial, it is the investigator or in case of post-marketing trial, it is either the physician or the prescriber or the patient himself who reports the adverse event or any drug-related problem. Pharmacovigilance case processing helps to get clear information regarding the drug and outcomes by using various software technologies. Arugs database, cemflow, vigibase and ICSR are few software used nowadays. Case processing helps to monitor and track all serious adverse events, and medically significant ADRs and other medical related product information followed by timely processing and reporting of such information according with company and regulatory reporting.</p> Anil Kumar Y, Divya A, Sayamma B, Karishma Sk, Ravi Kumar Konda, Santhosh Kumar Ch Copyright (c) 2022 Tue, 02 Aug 2022 00:00:00 +0530